What is molecular profiling, and how is it reshaping cancer treatment?

Molecular profiling extends traditional cancer classification by incorporating specific genetic and molecular alterations to better predict treatment response.

In our recent video, created by project partner CERTH, we focus on the clinical utility of tumour genomic profiling, explaining how analysing the genetic makeup of tumours helps predict treatment response and personalise care for better patient outcomes. The video explores barriers such as cost, access, and variability in patient response, and introduces CGI-Clinics as a collaborative effort to democratise genomic interpretation across Europe. Emphasis is placed on equipping both patients and clinicians with the knowledge to make informed, equitable treatment decisions.

Delivered in plain language and structured for clarity, with an emphasis on clinical relevance and patient-centered care, this video aims to be a valuable educational resource, supporting clinicians in communicating complex genomic concepts with clarity and empathy.

Watch ‘Molecular Profiling in Oncology’ below for an informative overview:

To support open science and ensure long-term access, the video has been archived in Zenodo, an open-access repository that assigns a persistent DOI to each resource, making them citable, discoverable and permanently available. When citing this video, please use DOI 10.5281/zenodo.15846904

CERTH has also created a video ‘Artificial Intelligence in Oncology’, linked here. These educational resources reflect the CGI-Clinics project’s commitment to not only advancing technological capabilities in oncogenomics but also to humanising them through effective communication.